Structural and functional analysis of the hemagglutinin-esterase of infectious salmon anaemia virus
نویسندگان
چکیده
منابع مشابه
Genomic organization of infectious salmon anaemia virus.
The RNA genome segment order, nucleotide sequence and the putative encoded proteins were determined for infectious salmon anaemia virus (ISAV). Eight segments of genomic viral RNA between 1.0 and 2.4 kb in length were identified. RNA segments 1-6 each had a predicted single open reading frame encoding the P1, PB1, NP, P2, P3 and HA proteins, respectively. Segment 7 encoded the P4/P5 proteins an...
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Infectious salmon anaemia (ISA) is a major disease of Atlantic salmon, Salmo salar, caused by an orthomyxovirus (ISAV). Increases in global aquaculture and the international movement of fish made it important to determine if Pacific salmon are at risk. Steelhead trout, Oncorhynchus mykiss, and chum, O. keta, Chinook, O. tshawytscha, coho, O. kisutch, and Atlantic salmon were injected intraperit...
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15 صفحه اولCloning and identification of the infectious salmon anaemia virus haemagglutinin.
Infectious salmon anaemia virus (ISAV) is an orthomyxo-like virus that causes serious disease in Atlantic salmon (Salmo salar). Like the orthomyxoviruses, ISAV has been shown to possess haemagglutinin (HA) activity. This study presents the cloning, expression and identification of the ISAV HA gene, which was isolated from a cDNA library by immunoscreening. The HA gene contained an ISAV-specific...
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ژورنال
عنوان ژورنال: Virus Research
سال: 2010
ISSN: 0168-1702
DOI: 10.1016/j.virusres.2010.03.020